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Brighton Collaboration
The Brighton Collaboration (BC), named after the city in England where the idea was first formulated, is an independent global vaccine safety research network for health care professionals. It is a non-profit partnership providing high-quality vaccine safety information.
The Brighton Collaboration was launched in 2000 as a voluntary international organization to facilitate the development, evaluation, and dissemination of high quality information about the safety of human vaccines. The idea of the collaboration started in 1999, following a presentation by Bob Chen at an international scientific vaccine conference in Brighton, U.K.. In his talk, he stressed the need to improve vaccine safety monitoring by developing internationally accepted standards.〔(Chen RT. Vaccine risks: real, perceived and unknown. Vaccine 1999 )〕 Among the members of the audience were Harald Heijbel, Ulrich Heininger, Tom Jefferson, and Elisabeth Loupi who approached Bob Chen after his presentation. The 5 of them decided to start the project to develop a common language and standardized research methodology to improve the accuracy of vaccine safety risk assessment modeled after the Cochrane Collaboration for evidence-based medicine
== Background ==
National and regional immunization coverage and the total numbers of vaccines administered is growing in all countries. Hundreds of millions of children and adolescents have been immunized globally.〔(World Health Organization. State of the World’s Vaccines and Immunization. May, 2010 )〕 The coming decade will be one of the most productive in the history of vaccine development.〔(Bill and Melinda Gates Foundation. Decade of Vaccines )〕 In countries with mature immunization programs, infection rates have fallen by 99%.〔(World Health Organization U. Global Immunization Vision and Strategy 2006 )〕 The global collaborative effort to implement immunization programs is estimated to save (2-3 millions of deaths each year ).〔(Duclos P, Okwo-Bele JM, Gacic-Dobo M, Cherian T. Global immunization: status, progress, challenges and future ), BMC Int Health Hum Rights. 2009;9 Suppl 1:S2.〕
With the increase of vaccines around the world, there is an increased responsibility to carefully monitor and investigate their safety.〔(World Health Organization. Immunization Safety )〕〔Vaccine Controversy〕 Today, vaccine safety concerns happen in all areas of the globe. When these concerns go unaddressed, whether they are well founded or not, they can have devastating consequences for immunization programs, and thus the lives of millions. If there is a real safety issue with a vaccine given to healthy individuals, identification, communication, as well as a timely and reliable public health response and regulatory action is the collective ethical mandate. For a global immunization program to be successful and sustainable, concerted safety monitoring must develop alongside of it.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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